With selected press releases of the member institutes we inform you here about their research on ageing.

  1. Inflammatory processes impair nerve regeneration in old age
    19.10.2018 · FLI Leibniz Institute on Aging - Fritz Lipmann Institute

    The regenerative capacity of the nervous system declines during aging; the risk to develop nerve pathologies increases. Researchers of the Leibniz Institute on Aging (FLI) in Jena investigated the regeneration of aging nerves in...

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  2. New function of “kidney-gene” – WT1 plays a role in the central nervous system and controls movement
    16.10.2018 · FLI Leibniz Institute on Aging - Fritz Lipmann Institute

    The WT1 gene fulfills a central role in the development of a healthy, proper functioning kidney. Mutations in WT1 lead to impairments in kidney development and cause Wilms tumors, a pediatric kidney cancer. Researchers of the...

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  3. Increased Blood Flow triggers Liver Regeneration
    16.10.2018 · DDZ German Diabetes Center

    The liver is one of the most important human organs. It is essential for metabolism, blood detoxification and the functioning of the immune system. Moreover, the liver is the only organ which can fully regenerate its cell mass...

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  4. 1. Jena Aging Meeting (JAM) from September 6-8 in Jena
    10.09.2018 · LRA Healthy Ageing

    Around 200 researchers from 16 countries meet in Jena from September 6-8 at the international “Jena Aging Meeting” to discuss latest research results and developments in the field of aging research. The very first JAM is...

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  5. More than just a DNA repair deficiency syndrome – impaired acetylation in Cockayne syndrome B
    31.08.2018 · IUF – Leibniz Research Institute for Environmental Medicine

    By studying the skin phenotype of the hereditary disease Cockayne syndrome researchers at the IUF and HHU Düsseldorf have found a mechanism which can prevent the loss of subcutaneous fat, i.e. one of the cardinal symptoms of...

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  6. Scientists of the LRA Healthy Ageing at the University of California, Berkeley
    28.08.2018 · LRA Healthy Ageing

    Scientists of the LRA Healthy Ageing represented the research alliance at an interdisciplinary meeting of ageing researchers in Berkeley on August 17th. The Center for Research and Education on Aging (CREA) at the UC Berkeley...

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  7. New Biomarkers of Inflammation Identified as Risk Factors for Neuropathy
    24.08.2018 · DDZ Deutsches Diabetes-Zentrum

    Although many patients suffer from polyneuropathy, relatively little is currently known about its development, which also limits the therapeutic options. It is known that inflammatory processes contribute to other diabetic...

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  8. A molecular switch may serve as new target point for cancer and diabetes therapies
    13.08.2018 · FMP Leibniz-Forschungsinstitut für Molekulare Pharmakologie

    If certain signaling cascades are misregulated, diseases like cancer, obesity and diabetes may occur. A mechanism recently discovered by scientists at the Leibniz- Forschungsinstitut für Molekulare Pharmakologie (FMP) in Berlin...

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  9. Alexander von Humboldt Research Fellow at FLI
    13.08.2018 · FLI Leibniz Institute on Aging - Fritz Lipmann Institute

    Ukrainian cell biologist Dr. Yuliya Kurlishchuk has received a research fellowship for postdocs from the Alexander von Humboldt Foundation. With this funding, she is now a guest at the Leibniz Institute on Aging – Fritz Lipmann...

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  10. Aggressive tumors - New regulator in breast cancer cells discovered
    06.08.2018 · FLI Leibniz Institute on Aging - Fritz Lipmann Institute

    Triple-negative breast cancer is a particularly aggressive form of breast cancer. Here, important receptors are missing, which often serve as targets for treatments. Thus, these tumors are unlikely to respond to current...

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  11. Back-to-back: Current Studies on the Longevity of Naked Mole-Rats
    02.08.2018 · FLI Leibniz Institute on Aging - Fritz Lipmann Institute

    Naked mole-rats can live considerably longer than other rodents like mouse, rat or guinea pig. This makes them outliers among mammals, just as humans with their maximum lifespan of about 120 years. The identification of genetic...

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  12. Heart Attack and Stroke Risk Also Elevated in Women with Obesity Who Are Metabolically Healthy
    31.05.2018 · DIfE German Institute of Human Nutrition Potsdam-Rehbrück

    Women with obesity are at increased risk of cardiovascular disease, even if they are considered to be metabolically healthy. Moreover, women of normal weight are at risk of heart attack or stroke if they suffer from a metabolic...

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  13. Less is more? Gene switch for healthy aging found
    28.05.2018 · FLI Leibniz Institute on Aging - Fritz Lipmann Institute

    Aging is associated with an increase in frailty and age related-diseases. A calorie-restricted diet is known to alleviate these age-related conditions. Researchers from the European Research Institute for the Biology of Ageing...

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  14. Surviving in starvation - New mechanism for cell preservation discovered
    15.05.2018 · FLI Leibniz Institute on Aging - Fritz Lipmann Institute

    Scientists from the Leibniz Institute on Aging – Fritz Lipmann Institute (FLI) in cooperation with the Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA, discovered a new mechanism that is important for...

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  15. Back to sleep: How SETD1A takes blood stem cells to rest
    08.05.2018 · FLI Leibniz Institute on Aging - Fritz Lipmann Institute

    In old age, humans increasingly suffer from infections. In such a case, blood stem cells that are usually inactive are activated in order to produce as many blood and immune cells as needed to fight the infection. However, every...

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  16. Old and Healthy: Researchers Find Novel Genes for Longevity in Mammals
    10.04.2018 · FLI Leibniz Institute on Aging - Fritz Lipmann Institute

    The genetic basis of lifespan determination is poorly understood. Most research has been done on short-lived animals, and it is unclear if these insights can be transferred to long-lived mammals like humans. By comparing genes of...

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  17. Cognitive impairment in the elderly – What is the role of air pollution and lung function?
    19.03.2018 · IUF Leibniz Research Institute for Environmental Medicine

    A study from scientists at IUF – Leibniz Research Institute for Environmental Medicine in Düsseldorf, Germany, published in the European Respiratory Journal, indicates that poor lung function is not only a risk factor for...

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  18. Additional 5 Million Euro Funding for Aging Research in Jena, Germany
    09.03.2018 · FLI Leibniz Institute on Aging - Fritz Lipmann Institute

    The Leibniz Institute on Aging (FLI) in Jena, Germany, was approved 5 million EUR additional funding by the German Joint Science Conference (Gemeinsame Wissenschaftskonferenz, GWK), which thus implemented a proposal by the Senate...

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  19. Cancer or degenerative diseases?
    31.01.2018 · FLI Leibniz Institute on Aging

    Above the age of 50, the most likely causes of death are cancer and degenerative diseases such as heart failure, dementia or diabetes. Since life expectancy has been considerably growing over the last 150 years, the frequency of...

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  20. Molecular Chaperones Shown to Assist in the Fight against Huntington Disease
    12.12.2017 · FMP Leibniz-Forschungsinstitut für Molekulare Pharmakologie

    Huntington’s disease is a neurodegenerative disease. It is always fatal. The disease is caused by a defect in the Huntingtin gene. To this day, no therapy will put a stop to the insidious disintegration of brain cells....

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