Leibniz-Forschungsverbund
Gesundes Altern

© FLI / Foto: Anna Schroll

Gemeinsame Publikationen

Nacktmullprojekt (IZW und FLI)

Thieme R, Kurz S, Kolb M, Debebe T, Holtze S, Morhart M, Huse K, Szafranski K, Platzer M, Hildebrandt TB, Birkenmeier G. (2015): Analysis of Alpha-2 Macroglobulin from the Long-Lived and Cancer-Resistant Naked Mole-Rat and Human Plasma. PLoS One 10(6), e0130470.

Henning Y, Vole C, Begall S, Bens M, Broecker-Preuss M, Sahm A, Szafranski K, Burda H, Dammann P. (2014): Unusual ratio between free thyroxine and free triiodothyronine in a long-lived mole-rat species with bimodal ageing. PLoS One 19;9(11), e113698.

Roellig K, Drews B, Goeritz F, Hildebrandt TB. (2011): The long gestation of the small naked mole-rat (Heterocephalus glaber RÜPPELL, 1842) studied with ultrasound biomicroscopy and 3D-ultrasonography. PLoS One 6, e17744.

Yu C, Li Y, Holmes A, Szafranski K, Faulkes CG, Coen CW, Buffenstein R, Platzer M, de Magalhães JP, Church GM. (2011): RNA sequencing reveals differential expression of mitochondrial and oxidation reduction genes in the long-lived naked mole-rat when compared to mice. PLoS One 6, e26729.

Dziegelewska M, Holtze S, Vole C, Wacher U, Menzel U, Morhart M, Groth M, Szafranski K, Sahm A, Sponholz C, Dammann P, Huse K, Hildebrandt T, Platzer M (2016): Low sulfide levels and high degree of cystathionine ß-synthase (CBS) activiation by S-adenosylmethionine (SAM) in the long-lived naked mole-rat. Rewdox Biol. 8:192-198. dio: 10.1016/j.redox.2016.01.008.

Bens M, Sahm A, Groth M, Jahn N, Morhart M, Holtze S, Hildebrandt TB, Platzer M, Szafranski K (2016): FRAMA: from RNA-seq data tzo annotated mRNA assemblies. BMC Genomics 17(1):54. doi: 10.1186/s12864-015-2349-8.

FLI mit DIfE

Mansfeld J, Urban N, Priebe S, Groth M, Frahm C, Hartmann N, Gebauer J, Ravichandran 1, Dommaschk 3, Schmeisser 3, Kuhlow D, Monajembashi S, Bremer-Streck S, Hemmerich P, Kiehntopf M, Zamboni N, Englert C, Guthke R, Kaleta C, Platzer M, Sühnel J, Witte OW, Zarse K, Ristow M (2015): Branched-chain amino acid catabolism is a conserved regulator of physiological ageing. Nat Commun. 6:10043. doi: 10.1038/ncomms10043.

Weimer S, Priebs J, Kuhlow D, Groth M, Priebe S, Mansfeld J, Merry TL, Dubuis S, Laube B, Pfeiffer AF, Schulz TJ, Guthke R, Platzer M, Zamboni N, Zarse K, Ristow M (2014): D-Glucosamine supplementation extends life span of nematodes and of ageing mice. Nat Commun. 2014 Apr 8;5:3563. doi: 10.1038/ncomms4563.

DIfE mit DDZ

Lubura M, Hesse D, Kraemer M, Hallahan N, Schupp M, von Löffelholz C, Kriebel J, Rudovich N, Pfeiffer A, John C, Scheja L, Heeren J, Koliaki C, Roden M, Schürmann A. (2015): Diabetes prevalence in NZO females depends on estrogen action on liver fat content. Am J Physiol Endocrinol Metab. 309(12):E968-80. doi: 10.1152/ajpendo.00338.2015.

Hattersley JG1, Pfeiffer AF, Roden M, Petzke KJ, Hoffmann D, Rudovich NN, Randeva HS, Vatish M, Osterhoff M, Goegebakan Ö, Hornemann S, Nowotny P, Machann J, Hierholzer J, von Loeffelholz C, Möhlig M, Arafat AM, Weickert MO (2014): Modulation of amino acid metabolic signatures by supplemented isoenergetic diets differing in protein and cereal fiber content. J Clin Endocrinol Metab. 99(12):E2599-609. doi: 10.1210/jc.2014-2302.

Nowotny B, Zahiragic L, Bierwagen A, Kabisch S, Groener JB, Nowotny PJ, Fleitmann AK, Firouzi P, Herder C, Pacini G, Erlund I, Landberg R, Haering HU, Pfeiffer AF, Nawroth PP, Roden M (2016): Erratum to: Low-energy diets differing in fibre, red meat and coffee intake equally improve insulin sensitivity in type 2 diabetes: a randomised feasibility trial. Diabetologia.  [Epub ahead of print]

FLI mit FMP

Zhang SC, Gremer L, Heise H, Janning P, Shymanets A, Cirstea IC, Krause E, Nürnberg B, Ahmadian MR (2014): Liposome reconstitution and modulation of recombinant prenylated human Rac1 by GEFs, GDI1 and Pak1. PLoS One. 9(7):e102425. doi: 10.1371/journal.pone.0102425.

FLI mit IUF

Scharf A, Gührs KH, von Mikecz A ( 2016): Anti-amyloid compounds protect from silica nanoparticle-induced neurotoxicity in the nematode C. elegans.Nanotoxicology. 10(4):426-35. doi: 10.3109/17435390.2015.1073399.

Zoch A, Mayerl S, Schulz A, Greither T, Frappart L, Rübsam J, Heuer H, Giovannini M, Morrison H (2015): Merlin Isoforms 1 and 2 Both Act as Tumour Suppressors and Are Required for Optimal Sperm Maturation. PLoS One. 2015 Aug 10;10(8):e0129151. doi: 10.1371/journal.pone.0129151.

Li H, Moll J, Winkler A, Frappart L, Brunet S, Hamann J, Kroll T, Verlhac MH, Heuer H, Herrlich P, Ploubidou A (2015): RHAMM deficiency disrupts folliculogenesis resulting in female hypofertility. Biol Open. 4(4):562-71. doi: 10.1242/bio.201410892.

Mayerl S, Liebsch C, Visser TJ, Heuer H (2015): Absence of TRH receptor 1 in male mice affects gastric ghrelin production. Endocrinology. 156(2):755-67. doi: 10.1210/en.2014-1395.

Kersseboom S, Horn S, Visser WE, Chen J, Friesema EC, Vaurs-Barrière C, Peeters RP, Heuer H, Visser TJ (2014): In vitro and mouse studies supporting therapeutic utility of triiodothyroacetic acid in MCT8 deficiency. Mol Endocrinol. 28(12):1961-70. doi: 10.1210/me.2014-1135.

Müller J, Heuer H (2014): Expression pattern of thyroid hormone transporters in the postnatal mouse brain. Front Endocrinol (Lausanne). 5:92. doi: 10.3389/fendo.2014.00092.

Müller J, Mayerl S, Visser TJ, Darras VM, Boelen A, Frappart L, Mariotta L, Verrey F, Heuer H. Tissue-specific alterations in thyroid hormone homeostasis in combined Mct10 and Mct8 deficiency. Endocrinology. 155(1):315-25. doi: 10.1210/en.2013-1800.

LIN mit FMP

Fidzinski P, Korotkova T, Heidenreich M, Maier N, Schuetze S, Kobler O, Zuschratter W, Schmitz D, Ponomarenko A, Jentsch TJ (2015): KCNQ5 K(+) channels control hippocampal synaptic inhibition and fast network oscillations.Nat Commun. 6:6254. doi: 10.1038/ncomms7254.

Rehberg K, Kliche S, Madencioglu DA, Thiere M, Müller B, Meineke BM, Freund C, Budinger E, Stork O (2014): The serine/threonine kinase Ndr2 controls integrin trafficking and integrin-dependent neurite growth. J Neurosci. 34(15):5342-54. doi: 10.1523/JNEUROSCI.2728-13.2014.

DRFZ mit IUF

Neumann C, Heinrich F, Neumann K, Junghans V, Mashreghi MF, Ahlers J, Janke M, Rudolph C, Mockel-Tenbrinck N, Kühl AA, Heimesaat MM, Esser C, Im SH, Radbruch A, Rutz S, Scheffold A. (2014): Role of Blimp-1 in programing Th effector cells into IL-10 producers.J Exp Med. 211(9):1807-19. doi: 10.1084/jem.20131548.

DRFZ mit BIPS

Winter Y, Pieper L, Klotsche J3, Riedel O, Wittchen HU. ( 2016): Obesity and Abdominal Fat Markers in Patients with a History of Stroke and Transient Ischemic Attacks. J Stroke Cerebrovasc Dis. pii: S1052-3057(15)00694-1. doi: 10.1016/j.jstrokecerebrovasdis.2015.12.026. [Epub ahead of print].

Ritz T, Wittchen HU, Klotsche J, Mühlig S, Riedel O, sap-NEEDs study group *. (2016): Asthma Trigger Reports Are Associated with Low Quality of Life, Exacerbations, and Emergency Treatments. Ann Am Thorac Soc. 13(2):204-11. doi: 10.1513/AnnalsATS.201506-390OC.

Riedel O, Klotsche J, Wittchen HU; GEPAD study group (2014): Motor impairment, depression, dementia: which forms the impression of disease severity in Parkinson's disease? Parkinsonism Relat Disord. 20(12):1365-70. doi: 10.1016/j.parkreldis.2014.09.025.

IUF mit DDZ

Teichert T, Hellwig A, Peßler A, Hellwig M, Vossoughi M, Sugiri D, Vierkötter A, Schulte T, Freund J, Roden M, Hoffmann B, Schikowski T, Luckhaus C, Krämer U, Henle T, Herder C (2015): Association between Advanced Glycation End Products and Impaired Fasting Glucose: Results from the SALIA Study. PLoS One. 10(5):e0128293. doi: 10.1371/journal.pone.0128293. eCollection 2015.

Raumplanung (ILS und IÖR)

Banse J, Berndgen-Kaiser A, Deilamnn C, Fox-Kämper R, Möbius M (2015): Wohnsituation und Wohnwünsche älterer Menschen in ost- und westdeutschen Städten. Stuttgart, Fraunhofer IRB Verlag.

 

Publikationen der Institute

Im Folgenden finden Sie die wichtigsten Publikationen der Mitgliedsinstitute zum Thema Alternsforschung. Die Liste ist nach den Sektionen der Leibniz-Gemeinschaft sortiert:

Sektion A: Geisteswissenschaften und Bildungsforschung

Sektion B: Wirtschafts- und Sozialwissenschaften, Raumwissenschaften

Sektion C: Lebenswissenschaften

Sektion D: Mathematik, Natur- und Ingenieurwissenschaften


Sektion A: Geisteswissenschaften und Bildungsforschung


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Sektion B: Wirtschafts- und Sozialwissenschaften, Raumwissenschaften






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Sektion C: Lebenswissenschaften








Leibniz-Institut für Neurobiologie (LIN)
Prof. Dr. Eckart D. Gundelfinger

Frischknecht R, Heine M, Perrais D, Seidenbecher CI, Choquet D, Gundelfinger ED (2009): Brain extracellular matrix affects AMPA receptor lateral mobility and short-term synaptic plasticity. Nat Neurosci 12:897-904, DOI: 10.1038/nn.2338.

Karpova A, Mikhaylova M, Bera S, Bär J, Reddy PP, Behnisch T, Rankovic V, Spilker C, Bethge P, Sahin J, Kaushik R, Zuschratter W, Kähne T, Naumann M, Gundelfinger ED, Kreutz MR (2013): Encoding and Transducing the Synaptic or Extrasynaptic Origin of NMDA Receptor Signals to the Nucleus. Cell 152(5):1119-1133, DOI: 10.1016/j.cell.2013.

Lison H, Happel MF, Schneider F, Baldauf K, Kerbstat S, Seelbinder B, Schneeberg J, Zappe M, Goldschmidt J, Budinger E, Schroder UH, Ohl FW, Schilling S, Demuth HU, Scheich H, Reymann KG, Ronicke R (2014): Disrupted cross-laminar cortical processing in beta amyloid pathology precedes cell death. Neurobiol Dis 63:62-73, DOI: 10.1016/j.nbd.2013.

Rönicke R, Mikhaylova M, Ronicke S, Meinhardt J, Schroder UH, Fandrich M, Reiser G, Kreutz MR, Reymann KG (2011): Early neuronal dysfunction by amyloid beta oligomers depends on activation of NR2B-containing NMDA receptors. Neurobiol Aging 32:2219-2228, DOI: 10.1016/j.neurobiolaging.2010.01.011.

Schott B, Niehaus L, Wittmann B, Schutze H, Seidenbecher C, Heinze H, Duzel E (2007): Ageing and early-stage Parkinson's disease affect separable neural mechanisms of mesolimbic reward processing. Brain 130:2412-2424.




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Sektion D: Mathematik, Natur- und Ingenieurwissenschaften

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