Leibniz Research Alliance
Healthy Ageing

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From Mice to Men - Determinants of Learning and Plasticity in Ageing

Human ageing is usually accompanied by decreased mental abilities. These are associated with neural alterations in different brain areas in the elderly, including decreases in neural plasticity and neural reorganization important for learning. Our focus group aims to identify factors that influence neural plasticity and mental abilities in ageing as well as to investigate the close interrelationship between ageing, neural plasticity and genetic and external factors. As studies on ageing are often limited to correlational designs, we will employ experiments on transgenic mice to gain deeper insights into the biological and neural mechanisms that determine mental abilities over the lifespan. Ultimately, we aim to identify and establish intervention strategies in cross-species designs (for example, physically and cognitively demanding training activities) to (re-)induce plasticity and hence to preserve and improve cognitive functioning in older age.

Period: 1. Januar 2017 - 31. Dezember 2018

Speaker:
PD Dr. Stephan Getzmann
Leibniz Research Centre for Working Environment and Human Factors (IfADo)
Phone: ++49 (0)231 / 10 84 338
getzmann(at)ifado.de

Contact:
Dr. Oliver Kobald
Leibniz Research Centre for Working Environment and Human Factors (IfADo)
Phone: ++49 (0)231 / 10 84 369
kobald(at)Ifado.de

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