Read in the second edition:
1. The up- and downside of caloric restriction for ageing and health
Besides improving the functionality of stem cells in mice, a caloric restriction also leads to a fatal weakening of their immune system – counteracting the life-lengthening effect of a diet.
2. Patients in completely locked-in state communicate
Researchers at the University of Tübingen could break through the silence of completely locked-in patients. Since they are able to hear, the researchers used oxygenation levels of blood in the brain to communicate with the patients.
3. Neuronal protein influences spatial learning
Jacob is a neuronal protein that plays an important role as a mediator of signals between synapses and cell nucleus. Researchers in Magdeburg showed that Jacob influences spatial learning processes.
4. Drug management of elderly patients with chronic myeloid leukemia
The German CML Study Group investigated the influence of age on the drug treatment on patients with chronic myeloid leukemia (CML). They suggest that the standard dose of 400 mg per day might be too low for elder patients.
You find the second edition of „Healthy Ageing – Forschung aus erster Hand“ at www.leibniz-healthy-ageing.de. Or you can order the printed edition from
Astrid van der Wall
Coordinator LRA Healthy Ageing
Leibniz Institute on Aging (FLI)
D - 07745 Jena
The Leibniz Research Alliance (LRA) Healthy Ageing is a network of 21 Leibniz Institutes. It brings together researchers from the fields of biology, medicine, psychology, education, sociology and economics. Their task is to research the factors that underlie the ageing process. They do this within interdisciplinary projects, an approach that allows them to investigate every aspect of healthy ageing, to collaborate on applying for projects, and to share resources and knowledge.
The Leibniz Association connects 88 independent research institutions that range in focus from the natural, engineering and environmental sciences via economics, spatial and social sciences to the humanities. Leibniz institutes address issues of social, economic and ecological relevance. They conduct knowledge-driven and applied basic research, maintain scientific infrastructure and provide research-based services. The Leibniz Association identifies focus areas for knowledge transfer to policy-makers, academia, business and the public. Leibniz institutions collaborate intensively with universities – in the form of “Leibniz ScienceCampi” (thematic partnerships between university and non-university research institutes), for example – as well as with industry and other partners at home and abroad. They are subject to an independent evaluation procedure that is unparalleled in its transparency. Due to the importance of the institutions for the country as a whole, they are funded jointly by the Federation and the Länder, employing some 18,500 individuals, including 9,300 researchers. The entire budget of all the institutes is approximately 1.7 billion EUR.